Skip to main content Skip to footer
  • For Lease
75,000 SF Available for Lease 3Q 2022 Prime Cortex Location - #1
75,000 SF Available for Lease 3Q 2022 Prime Cortex Location - #2
75,000 SF Available for Lease 3Q 2022 Prime Cortex Location - #3
75,000 SF Available for Lease 3Q 2022 Prime Cortex Location - #4

For Lease

$26 / SF USD

Architecturally striking and built to Fortune 500 standards, 4300 Duncan is a future-forward workplace with technology and collaboration at its core. Infused with equal parts productivity and lifestyle, 4300 Duncan is situated at the center of the
Cortex Innovation Community; a gravitational hub for top global talent.


Cortex is a vibrant, 200-acre hub of business, innovation, and technology integrated into St. Louis’ historic Central West End and Forest Park Southeast neighborhoods, surrounded by nationally ranked universities and medical centers and abundant cultural and recreational assets. Cortex is a catalyst for innovation that brings together big-thinking problem solvers with state-of-the-art resources, facilities, and innovative programming to inspire and drive collaboration.